Navigating CMC constraints during clinical development

AC Immune and the neurodegenerative landscape :

Learn how proactive scenario planning helps teams anticipate constraints earlier, and turn cross-functional tension into faster, better decisions.

Scenario 1: Drug product switch during ongoing recruitment

• Compare the implications of switching DP within patient treatment schedules versus adapting recruitment to keep patients on a single DP process.
• Reveal the operational trade-offs behind each path, from supply continuity to patient scheduling and trial integrity.
• See how early constraint visibility supports decisions.

Scenario 2: Late-stage strategy and the shift to late-stage CMOs

• Understand why moving to late-stage CMOs often introduces hidden complexity, longer timelines, and cost escalation.
• Anticipate capacity, tech transfer, and manufacturing readiness constraints before they impact your clinical strategy.
• Bring late-stage considerations into trial design early, without slowing down execution.

What this enables: discover how N-SIDE helps create a win-win between Clinical and CMC teams by making interdependencies explicit, aligning plans earlier, and enabling faster, more resilient execution.

Live Q&A: bring your toughest clinical–CMC planning challenges and discuss practical approaches with the speakers.